Studies of plasma protein synthesis by peripheral cells from normal persons and patients with infectious mononucleosis.
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منابع مشابه
Evaluation of IL-17 and IL-10 Production in Infectious Mononucleosis in EBV Patients
Epstein–Barr virus is primarily the cause of acute infectious mononucleosis and can also cause lymphoma and autoimmune diseases. Th17 cells, which are a unique subset of ThCD4+ cells, direct the infection toward inflammation through production of inflammatory cytokine IL-17. In contrast, Treg Foxp3 cells inhibit inflammation through secretion of anti-inflammatory cytokine IL-10, leading to chro...
متن کاملTissue Culture of Cells Already in Dna Synthesis from Patients with Infectious Mononucleosis.
T HE PROLIFERATIVE capacity of smalland medium-sized lymphocytes in peripheral blood is now well established.25 These cells begin DNA synthesis and divide in tissue culture in response to a variety of mitosisstimulating agents. The most widely studied of these agents is phytohemagglutinin. Few or no mitosis are observed in cultures of normal peripheral lymphocytes when such a mitosis-stimulatin...
متن کاملFine structure of leukocytes in infectious mononucleosis: in vivo and in vitro studies.
T HE OCCURRENCE of heterophile antibodies and morphologic abnormalities in circulating mononuclear cells which produce immunoglobulins have focused the attention of immunologists and hematologists on the clinical syndrome of infectious mononucleosis. The unique morphologic features of the peripheral leukocytes found in this syndrome have been emphasized in numerous descriptions of observations ...
متن کاملStructural changes in the deoxyribonucleoprotein (DNP) complex of leukocytes from patients with infectious mononucleosis.
T HE FLUORESCENT BASIC DYE ACRIDINE ORANGE (AO) predominantly binds to negatively charged phosphate groups in the nucleoprotein complexes.1 Nondividing leukocytes of peripheral blood normally have a low number of binding sites in DNP accessible to AO but following administration of PHA, they exhibit a pronounced increase in AO binding24 as determined by fluorescence intensity measurements on in...
متن کاملDNA and RNA Synthesis of Circulating Atypical Lymphocytes in Infectious
I T IS NOW generally agreed that the atypical mononuclear cells associated with infectious mononucleosis are members of the lymphocyte family,”2 but little is known about physiologic differences that may exist between the abnormal cells and normal lymphocytes. One approach to an understanding of such differences has been the study of nucleic acid synthesis. Using radioautographic technics, Gavo...
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عنوان ژورنال:
- Blood
دوره 32 2 شماره
صفحات -
تاریخ انتشار 1968